THROMBOSIS AND HEMOSTASIS Mitochondrial dysfunction in antiphospholipid syndrome: implications in the pathogenesis of the disease and effects of coenzyme Q10 treatment
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چکیده
Mitochondrial dysfunction in antiphospholipid syndrome: implications in the pathogenesis of the disease and effects of coenzyme Q10 treatment *Carlos Perez-Sanchez,1 *Patricia Ruiz-Limon,1 Maria Angeles Aguirre,1 Maria Laura Bertolaccini,2 Munther A. Khamashta,3 Antonio Rodriguez-Ariza,1 Pedro Segui,1 Eduardo Collantes-Estevez,1 Nuria Barbarroja,4 Husam Khraiwesh,5 Jose Antonio Gonzalez-Reyes,5 Jose Manuel Villalba,5 Francisco Velasco,1 Maria Jose Cuadrado,3 and Chary Lopez-Pedrera1
منابع مشابه
Novel considerations in the pathogenesis of the antiphospholipid syndrome: involvement of the tissue factor pathway of blood coagulation.
The antiphospholipid syndrome (APS) is characterized by clinical manifestations such as venous and arterial thrombosis, thrombocytopenia and/or recurrent pregnancy loss, as well as the persistent presence of laboratory markers of antiphospholipid (aPL) antibodies detected in laboratory assays. Though it is generally accepted that aPL antibodies, such as anticardiolipin (aCL), anti-beta2 glycopr...
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